The Heart-ACT Programs

The Heart-ACT programs include a pilot study, Heart Health After Cancer Treatment (Heart-ACT Cancer) program aimed at reducing heart disease risk after cancer treatment in breast cancer survivors and the Heart-ACT Cardiac program, which is a randomized trial of a tailored cardiac rehab program delivered in a safety net setting as compared to usual care referral to cardiac rehab.


Heart-ACT Cancer

After surviving breast cancer, many people want to stay healthy but aren’t sure how to do it. Breast cancer survivors have a higher risk of having heart problems in the future, which makes it even more important to stay healthy. 

Investigators at Zuckerberg San Francisco General Hospital and the University of California, San Francisco worked with breast cancer survivors to create the HEART-ACT program to help improve health after cancer treatment. The program is 12 weeks long and is personalized to the individual. It includes exercise, health coaching, and education on physical activity, healthy eating, heart disease risk, and emotional wellbeing.

Please see our Resources page for helpful program resources. Click here for more information about the study.


Heart-ACT Cardiac

Cardiac rehabilitation is an exercise and health behavior counseling program for people with cardiovascular disease. However, many people who would benefit from cardiac rehab don't utilize it, including women, people from racial/ethnic minority groups, lower socioeconomic groups, and Medicare beneficiaries. 

We are testing a tailored cardiac rehabilitation program among safety net patients at Zuckerberg San Francisco General Hospital, and are comparing a tailored approach in a community health setting versus referral to an outside cardiac rehabilitation program.

The Heart-ACT Cardiac study builds on the intervention from the Heart-ACT Cancer program. Recruitment began in September 2025, and we are targeting 100 participants.

Click here for more information about the study.


This project is supported by a gift to UCSF from the Krueger v. Wyeth settlement as part of SYRMOUNT.

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