The Heart Health After Cancer Treatment (Heart-ACT Cancer) study is a pilot study of a multi-disciplinary health behavior intervention in people with a history of breast cancer to reduce heart disease risk after cancer treatment.
Program Design
Between November 2023 and March 2025 we recruited 50 participants (24 English-speaking, 11 Spanish-Speaking and 15 Cantonese-speaking) to participate in the study intervention, follow-up visits, and exit interviews. These participants completed a 12-week program that included an individualized assessment, goal, and plan for each component of the program. Follow-up for outcomes will occur at 3 months, 6 months, and 12 months. Program components include:
- Physical Activity
- Nutrition
- Emotional Wellbeing
- Cardiovascular Risk
- Survivorship
- Other items tailored to the individual as needed
Follow-up will continue until March 2026.
Aims and Hypotheses
We hypothesize that we will be able to calculate change in six-minute walk distance (6MWD) and change in quality of life (PROMIS Global Health Mental and Physical Scales) at 12 months in at least 75% of participants.
Secondary aims include establishing preliminary data on changes in objective and patient-reported measured including 6MWD, quality of life, health behaviors (medication adherence, physical activity, healthy eating), cognitive function, and potential mechanisms of action of the intervention including self-efficacy, social isolation, and optimism.
IRB Number: 22-37980